X chromosome reactivation initiates in nascent primordial germ cells in mice.

During primordial germ cell (PGC) development, epigenetic reprogramming events represented by X chromosome reactivation and erasure of genomic imprinting are known to occur. Although precise timing is not given, X reactivation is thought to take place over a short period of time just before initiati...

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Bibliographic Details
Main Authors: Michihiko Sugimoto, Kuniya Abe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1950944?pdf=render