Biohybrid -Se-S- Coupling Reactions of an Amino Acid Derived Seleninate

We describe the synthesis of the N-(2-seleninatoethyl) amide of N-Boc-phenylalanine, serving here as a peptide model, and its reductive coupling reactions under mild conditions with unprotected thiouridine and glutathione. Selenosulfide products such as these comprise reversibly conjugated bio-compo...

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Bibliographic Details
Main Authors: Zhexun Sun, Mohannad Abdo, Spencer Knapp
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/2/1963