Gingival Status of Kidney Transplanted Patients Referred to Shariati General Hospital, Tehran

• Main Authors: G. Ali Gholami, G. Ansari, K. Seyedan, H. Gholami
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2008-12-01
• Series: Frontiers in Dentistry
• Subjects: Gingival Overgrowth; Cyclosporine; Kidney Transplantation; Nifedipine; Periodontal Index
• Online Access: https://jdt.tums.ac.ir/index.php/jdt/article/view/162

Objective: The aim of the present study was to investigate the level of gingival over-growth (GO) in patients with kidney transplant. Materials and Methods: The target group of the study was the patients recently received kidney transplant and cyclosporine-A therapy. By a systematic case selection method, a total of 131 cases were included in the study, of whom 80 (61.6%) patients were male. The data was collected through interview with the patients as well as clinical assessment of their dental and periodontal indices. Gingival enlargement was recorded in terms of a 4-point scale from absence of enlargement to sever enlargement. Gilmore and Glickman plaque index was also recorded. Chi-square test served for statistical analysis. Results: The mean dose of the drug received was 203 mg (SD=75), with 191 mg (SD=71)in females and 209 mg (SD=77) in male individuals. GO was found in one-third of the pa-tients receiving CSA. Incidence of GO was found to be roughly equal in upper and lower jaw with no significant difference (P>0.05). Gingival enlargement was also found to be more prominent at the anterior region. Difference between two age groups was statistically significant (P<0.05). No Statistically significant difference was found between groups tak-ing different doses of the drug. Conclusion: Gingival overgrowth among the patients receiving kidney transplant and CSA therapy seems to vary according to such factors as age and gender, but not the dose of the drug taken.