The Calcium Channel α2δ1 Subunit: Interactional Targets in Primary Sensory Neurons and Role in Neuropathic Pain

The Calcium Channel α2δ1 Subunit: Interactional Targets in Primary Sensory Neurons and Role in Neuropathic Pain

Neuropathic pain is mainly triggered after nerve injury and associated with plasticity of the nociceptive pathway in primary sensory neurons. Currently, the treatment remains a challenge. In order to identify specific therapeutic targets, it is necessary to clarify the underlying mechanisms of neuro...

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Bibliographic Details
Main Authors: Wenqiang Cui, Hongyun Wu, Xiaowen Yu, Ting Song, Xiangqing Xu, Fei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuropathic pain
primary sensory neuron
Cavα2δ1
molecular target
peripheral sensitization
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.699731/full

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