Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure

Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure

Summary: Cytokinesis failure may result in the formation of polyploid cells, and subsequent mitosis can lead to aneuploidy and tumor formation. Tumor suppressor mechanisms limiting the oncogenic potential of these cells have been described. However, the universal applicability of these tumor-suppres...

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Bibliographic Details
Main Authors: Stephan U. Gerlach, Teresa Eichenlaub, Héctor Herranz
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718305357

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