Weak sharing of genetic association signals in three lung cancer subtypes: evidence at the SNP, gene, regulation, and pathway levels

Weak sharing of genetic association signals in three lung cancer subtypes: evidence at the SNP, gene, regulation, and pathway levels

Abstract Background There are two main types of lung cancer: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC has many subtypes, but the two most common are lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC). These subtypes are mainly classified by physiolo...

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Bibliographic Details
Main Authors: Timothy D. O’Brien, Peilin Jia, Neil E. Caporaso, Maria Teresa Landi, Zhongming Zhao
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Genome Medicine
Subjects:
GWAS
eQTL
Enhancer
Lung cancer subtype
Functional genomics
Pathway analysis
Online Access:http://link.springer.com/article/10.1186/s13073-018-0522-9

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