LAMP3 plays an oncogenic role in osteosarcoma cells partially by inhibiting TP53
Abstract Background Osteosarcoma (OS) is a common malignant tumor that predominantly occurs in adolescents. Its most common metastasis is to the lungs. As shown in our earlier study, lysosome-associated membrane glycoprotein 3 (LAMP3) is highly upregulated in metastatic OS. However, its role in the...
Main Authors: | Shaoxian Liu, Junyi Yue, Wei Du, Jian Han, Weidong Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
|
Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s11658-018-0099-8 |
Similar Items
-
TP53 in Biology and Treatment of Osteosarcoma
by: Kamil Jozef Synoradzki, et al.
Published: (2021-08-01) -
TP53 GENE MUTATIONS – FROM GUARDIAN OF THE GENOME TO ONCOGENE
by: Petar Babović, et al.
Published: (2010-03-01) -
LncRNA NR_027471 Functions as a ceRNA for miRNA-8055 Leading to Suppression of Osteosarcoma by Regulating the Expression of TP53INP1
by: Jiajia Chen, et al.
Published: (2020-09-01) -
Regulators of Oncogenic Mutant TP53 Gain of Function
by: Satomi Yamamoto, et al.
Published: (2018-12-01) -
The TP53 fertility network
by: Diego d'Avila Paskulin, et al.
Published: (2012-01-01)