Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2
We investigated whether, in view of its activity being expressed on both aspects of the endoplasmic reticulum (ER; dual membrane topology), diacylglycerol acyltransferase 1 (DGAT1) plays a distinctive role in determining the triglyceride (TAG) content of VLDL particles secreted by the liver. Mice in...
Main Authors: | Zehra Irshad, Nikola Chmel, Raghu Adya, Victor A. Zammit |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520326699 |
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