Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours

Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours

Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; <i>NPPC</i>) or its receptor guanylyl cyclase B (GC-B, <i>NPR2</i>) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mutations cause...

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Bibliographic Details
Main Authors: Samantha M. Mirczuk, Christopher J. Scudder, Jordan E. Read, Victoria J. Crossley, Jacob T. Regan, Karen M. Richardson, Bigboy Simbi, Craig A. McArdle, David B. Church, Joseph Fenn, Patrick J. Kenny, Holger A. Volk, Caroline P. Wheeler-Jones, Márta Korbonits, Stijn J. Niessen, Imelda M. McGonnell, Robert C. Fowkes
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
CNP
multiplex RT-qPCR
pituitary
somatotrope
acromegaly
feline
Online Access:https://www.mdpi.com/1422-0067/22/3/1076

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