Semi-Disparate Impact of Kinases GCN2 and PERK in Modulating the Dynamic Control Properties of eIF2 Pathway

The tumor microenvironment associated with deficiencies in nutrients and oxygen is important in observing the regulation of tumor progression. The aggressiveness of the tumor cells can be stimulated by exposing it to nutrient starvation and hypoxia. During nutrient starvation, activation of an integ...

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Bibliographic Details
Main Authors: Mohammad Farhan Khan, Sarah K. Spurgeon, Muaffaq M. Nofal, Xing-Gang Yan
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8719899/