The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway

The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway

Ovarian cancer is considered as one of the most fatal gynecologic malignancies. This work aimed to explore the effects and regulatory mechanism of Acyl-CoA medium-chain synthetase-3 (ACSM3, a subunit of CoA ligases) in ovarian cancer progression. As well as employing CCK-8 assay, clone formation ass...

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Bibliographic Details
Main Authors: Limei Yan, Zeping He, Wei Li, Ning Liu, Song Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
acyl-CoA medium-chain synthetase-3
integrin β1
proliferation
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.644840/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.644840/full

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