DNA vaccines for viral diseases

DNA plasmids encoding foreign proteins may be used as immunogens by direct intramuscular injection alone, or with various adjuvants and excipients, or by delivery of DNA-coated gold particles to the epidermis through biolistic immunization. Antibody, helper T lymphocyte, and cytotoxic T lymphocyte (...

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Bibliographic Details
Main Authors: J.J. Donnelly, J.B. Ulmer
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
CTL
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200010