Transcriptional factor FoxM1-activated microRNA-335-3p maintains the self-renewal of neural stem cells by inhibiting p53 signaling pathway via Fmr1

Transcriptional factor FoxM1-activated microRNA-335-3p maintains the self-renewal of neural stem cells by inhibiting p53 signaling pathway via Fmr1

Abstract Background New mechanistic insights into the self-renewal ability and multipotent properties of neural stem cells (NSCs) are currently under active investigation for potential use in the treatment of neurological diseases. In this study, NSCs were isolated from the forebrain of fetal rats a...

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Bibliographic Details
Main Authors: Jiaoying Jia, Yan Cui, Zhigang Tan, Min Liu, Yugang Jiang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Neural stem cells
Differentiation
FoxM1
MicroRNA-335-3p
Fmr1
Online Access:https://doi.org/10.1186/s13287-021-02191-2

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