CaMKII binding to GluN2B is important for massed spatial learning in the Morris water maze [v1; ref status: indexed, http://f1000r.es/3ud]

CaMKII binding to GluN2B is important for massed spatial learning in the Morris water maze [v1; ref status: indexed, http://f1000r.es/3ud]

Learning and memory as well as long-term potentiation (LTP) depend on Ca2+ influx through the NMDA-type glutamate receptor (NMDAR) and the resulting activation of the Ca2+ and calmodulin-dependent protein kinase (CaMKII). Ca2+ influx via the NMDAR triggers CaMKII binding to the NMDAR for enhanced Ca...

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Bibliographic Details
Main Authors: Ivar S. Stein, Michaela S. Donaldson, Johannes W. Hell
Format: Article
Language:English
Published: F1000 Research Ltd 2014-08-01
Series:F1000Research
Subjects:
Behavioral Neuroscience
Neuronal Signaling Mechanisms
Sensory Systems
Online Access:http://f1000research.com/articles/3-193/v1

Internet

http://f1000research.com/articles/3-193/v1

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