The Role of DNA Methylation in Transcriptional Regulation of Pro-Nociceptive Genes in Rat Trigeminal Ganglia

Epigenetic modulation by DNA methylation is associated with aberrant gene expression in sensory neurons, which consequently leads to pathological pain responses. In this study, we sought to investigate whether peripheral inflammation alters global DNA methylation in trigeminal ganglia (TG) and resul...

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Bibliographic Details
Main Authors: Guang Bai, Holly Ross, Youping Zhang, KiSeok Lee, Jin Y Ro
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Epigenetics Insights
Online Access:https://doi.org/10.1177/2516865720938677