Recyclable fluorous cinchona alkaloid ester as a chiral promoter for asymmetric fluorination of β-ketoesters

A fluorous cinchona alkaloid ester has been developed as a chiral promoter for the asymmetric fluorination of β-ketoesters. It has comparable reactivity and selectivity to the nonfluorous versions of cinchona alkaloids and can be easily recovered from the reaction mixture by simple fluorous solid-ph...

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Bibliographic Details
Main Authors: Wen-Bin Yi, Xin Huang, Zijuan Zhang, Dian-Rong Zhu, Chun Cai, Wei Zhang
Format: Article
Language:English
Published: Beilstein-Institut 2012-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.138