Inhibition of androgen receptor promotes CXC-chemokine receptor 7-mediated prostate cancer cell survival

Abstract The atypical C-X-C chemokine receptor 7 (CXCR7) has been implicated in supporting aggressive cancer phenotypes in several cancers including prostate cancer. However, the mechanisms driving overexpression of this receptor in cancer are poorly understood. This study investigates the role of a...

Full description

Bibliographic Details
Main Authors: James J. Hoy, Georgios Kallifatidis, Diandra K. Smith, Bal L. Lokeshwar
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02918-3