Hyperhomocysteinemia in men population of Novosibirsk

• Main Authors: Yu. P. Nikitin, O. V. Motina, Yu. I. Ragino, G. I. Simonova, Ya. V. Polonskaya, M. V. Ivanova, L. V. Cherbakova, S. K. Malyutina
• Format: Article
• Language: Russian
• Published: «FIRMA «SILICEA» LLC 2007-08-01
• Series: Российский кардиологический журнал
• Subjects: population study; hyperhomocysteinemia; coronary heart disease; low-density lipoproteins; α-tocopherol.
• Online Access: https://russjcardiol.elpub.ru/jour/article/view/2203

In population to the Siberian sample of men the prevalence of hyperhomocysteinemia (HHC) in winter-spring and in autumn seasons of year for the first time is studied, search of theoretically expected associations with CHD and with major factors of its risk is lead. It is executed a screening examination of representative sample of 243 men of 45-69 years with use of the standardized epidemiological and biochemical methods. The prevalence of HHC during the winter-spring period of year has made 43 %, during an autumn season of year has made 52 %. Statistically significant distinctions in the prevalence of HHC between seasons of year it is not revealed. It is not revealed correlation communications between a level of homocysteine blood and presence CHD. Positive correlation of homocysteinemia with the years, with a level of products of lipid peroxidation in IDI, and also its negative correlation with α-tocopherol level in LDL and with an index of weight of a body.