The Heat Shock Protein 27 Immune Complex Enhances Exosomal Cholesterol Efflux

The Heat Shock Protein 27 Immune Complex Enhances Exosomal Cholesterol Efflux

Previously, we demonstrated that Heat Shock Protein 27 (HSP27) reduces the inflammatory stages of experimental atherogenesis, is released by macrophage (MΦ) exosomes and lowers cholesterol levels in atherosclerotic plaques. Recently, we discovered that natural autoantibodies directed against HSP27 e...

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Bibliographic Details
Main Authors: Chunhua Shi, Daiana Alvarez-Olmedo, Yuan Zhang, Badal S. B. Pattar, Edward R. O’Brien
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomedicines
Subjects:
exosome
Heat Shock Protein 27
antibody
immune complex
Online Access:https://www.mdpi.com/2227-9059/8/8/290

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