Dual effects of targeting S100A11 on suppressing cellular metastatic properties and sensitizing drug response in gastric cancer

Dual effects of targeting S100A11 on suppressing cellular metastatic properties and sensitizing drug response in gastric cancer

Abstract Background S100A11 is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. The dysregulated expression of the S100A11 gene has been implicated in tumour metastasis. However, the role of S100A11 protein in tumour cell response to chemotherapeutic drugs has n...

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Bibliographic Details
Main Authors: Yuxin Cui, Liting Li, Zhilei Li, Jie Yin, Jane Lane, Jiafu Ji, Wen G. Jiang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cancer Cell International
Subjects:
S100A11
Gastric cancer
Clinical significance
Drug resistance
Adhesion
Invasion
Online Access:https://doi.org/10.1186/s12935-021-01949-1

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