Role of dendritic cells in the induction of lymphocyte tolerance

Role of dendritic cells in the induction of lymphocyte tolerance

The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces peripheral tolerance through mechanisms such as the secretion of soluble facto...

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Bibliographic Details
Main Authors: Fabiola eOsorio, Camila eFuentes, Mercedes N Lopez, Flavio eSalazar-Onfray, Fermín eGonzález
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
tolerance
Foxp3
regulatory T cells
DC-based immunotherapy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00535/full

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