Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction

Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction

In the era of combined antiretroviral therapy (cART), as infected individuals continue to have longer lifespans, there is also an increased prevalence of HIV-associated neurocognitive disorders (HAND). Inflammation is one of the underlying features of HAND, with the role of viral proteins and antire...

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Bibliographic Details
Main Authors: Ashutosh Tripathi, Annadurai Thangaraj, Ernest T. Chivero, Palsamy Periyasamy, Shannon Callen, Maria E. Burkovetskaya, Ming-Lei Guo, Shilpa Buch
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
combined antiretroviral therapy
lysosome
autophagy
microglial activation
neuroinflammation
Online Access:https://www.mdpi.com/2073-4409/8/10/1168

Internet

https://www.mdpi.com/2073-4409/8/10/1168

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