Impact of Chemotherapy Regimens on Normal Tissue Complication Probability Models of Acute Hematologic Toxicity in Rectal Cancer Patients Receiving Intensity Modulated Radiation Therapy With Concurrent Chemotherapy From a Prospective Phase III Clinical Trial

Impact of Chemotherapy Regimens on Normal Tissue Complication Probability Models of Acute Hematologic Toxicity in Rectal Cancer Patients Receiving Intensity Modulated Radiation Therapy With Concurrent Chemotherapy From a Prospective Phase III Clinical Trial

Purpose: To determine whether there are differences in bone marrow tolerance to chemoradiotherapy (CRT) between two chemotherapy regimens according to FOWARC protocol and how chemotherapy regimens affect radiation dose parameters and normal tissue complication probability (NTCP) modelings that corre...

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Bibliographic Details
Main Authors: Yikan Cheng, Yan Ma, Jian Zheng, Hua Deng, Xueqin Wang, Yewei Li, Xiaolin Pang, Haiyang Chen, Fang He, Lei Wang, Jianping Wang, Xiangbo Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
rectal cancer
chemoradiotherapy
hematologic toxicity
FOWARC
normal tissue complication probability (NTCP)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00244/full

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