l-Cystathionine Inhibits the Mitochondria-Mediated Macrophage Apoptosis Induced by Oxidized Low Density Lipoprotein

l-Cystathionine Inhibits the Mitochondria-Mediated Macrophage Apoptosis Induced by Oxidized Low Density Lipoprotein

This study was designed to investigate the regulatory role of l-cystathionine in human macrophage apoptosis induced by oxidized low density lipoprotein (ox-LDL) and its possible mechanisms. THP-1 cells were induced with phorbol 12-myristate 13-acetate (PMA) and differentiated into macrophages. Macr...

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Bibliographic Details
Main Authors: Mingzhu Zhu, Junbao Du, Siyao Chen, Angie Dong Liu, Lukas Holmberg, Yonghong Chen, Chunyu Zhang, Chaoshu Tang, Hongfang Jin
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
l-cystathionine
ox-LDL
macrophage
mitochondrial
oxidative stress
apoptosis
caspase-9
caspase-3
Online Access:http://www.mdpi.com/1422-0067/15/12/23059

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