Acid-base equilibria of 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid and its labeling with technetium-99m

Acid-base equilibria of 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid and its labeling with technetium-99m

The acid-base equilibria of a novel hepatobiliary imaging agent, 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid (DIIODIDA) were studied. The potentiometrically determined acidity constants of the second carboxylic group, amino and amide groups were pK2 = 2.52 ± 0.02; pK3 = 5.86 ± 0.06 a...

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Bibliographic Details
Main Authors:	S. VLADIMIROV, V. KAPETANOVIC, G. POPOVIC, M. S. JOVANOVIC, J. S. BRBORIC
Format:	Article
Language:	English
Published:	Serbian Chemical Society 2006-01-01
Series:	Journal of the Serbian Chemical Society
Subjects:	iminodiacetic acid analogues acidity constants hepatobiliary agent technetium-99m
Online Access:	http://www.shd.org.yu/HtDocs/SHD/Vol71/No1/JSCS_V71_No1-06.pdf

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