| Summary: | Objective: To study the effect of Azithromycin sequential therapy combined with Tanreqing
injection on serum sTREM-1, CK, G-CSF, IL-10, CRP and TNF-α in children with
mycoplasma pneumonia. Methods: A total of 80 children with mycoplasma pneumonia in
our hospital from June 2014 to September 2016 were enrolled in this study. The subjects
were divided into the control group (n=40) and the treatment group (n=40) randomly. The
control group were treated with Azithromycin sequential therapy, the treatment group were
treated with Azithromycin sequential therapy combined with Tanreqing injection. The two
groups were treated for 2 periods. The serum sTREM-1, CK, G-CSF, IL-10, CRP and TNF-α
levels of the two groups before and after treatment were compared. Results: There were
no significantly differences of the serum sTREM-1, CK, G-CSF, IL-10, CRP and TNF-α
levels of the two groups before treatment. The serum sTREM-1, CK, G-CSF, IL-10, CRP and
TNF-α levels of the two groups after treatment were significantly lower than before treatment,
and that of the treatment group were significantly lower than the control group. Conclusion:
Azithromycin sequential therapy combined with Tanreqing injection can significantly reduce
the serum sTREM-1, CK, G-CSF, IL-10, CRP and TNF-α levels of children with mycoplasma
pneumonia, have good clinical efficacy, and it was worthy clinical application.
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