4D treatment planning for scanned ion beams

<p>Abstract</p> <p>At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of motion, scanned ion beam therapy is not yet possible be...

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Main Authors: Rietzel Eike, Bert Christoph
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/2/1/24
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spelling doaj-d6417ddb6315428e857f6bc01048ae682020-11-25T00:05:19ZengBMCRadiation Oncology1748-717X2007-07-01212410.1186/1748-717X-2-244D treatment planning for scanned ion beamsRietzel EikeBert Christoph<p>Abstract</p> <p>At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of motion, scanned ion beam therapy is not yet possible because of interplay effects between scanned beam and target motion which can cause severe mis-dosage. We have started a project to treat tumors that are subject to respiratory motion. A prototype beam application system for target tracking with the scanned pencil beam has been developed and commissioned.</p> <p>To facilitate treatment planning for tumors that are subject to organ motion, we have extended our standard treatment planning system TRiP to full 4D functionality. The 4D version of TRiP allows to calculate dose distributions in the presence of motion. Furthermore, for motion mitigation techniques tracking, gating, rescanning, and internal margins optimization of treatment parameters has been implemented. 4D calculations are based on 4D computed tomography data, deformable registration maps, organ motion traces, and beam scanning parameters.</p> <p>We describe the methods of our 4D treatment planning approach and demonstrate functionality of the system for phantom as well as patient data.</p> http://www.ro-journal.com/content/2/1/24
collection DOAJ
language English
format Article
sources DOAJ
author Rietzel Eike
Bert Christoph
spellingShingle Rietzel Eike
Bert Christoph
4D treatment planning for scanned ion beams
Radiation Oncology
author_facet Rietzel Eike
Bert Christoph
author_sort Rietzel Eike
title 4D treatment planning for scanned ion beams
title_short 4D treatment planning for scanned ion beams
title_full 4D treatment planning for scanned ion beams
title_fullStr 4D treatment planning for scanned ion beams
title_full_unstemmed 4D treatment planning for scanned ion beams
title_sort 4d treatment planning for scanned ion beams
publisher BMC
series Radiation Oncology
issn 1748-717X
publishDate 2007-07-01
description <p>Abstract</p> <p>At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of motion, scanned ion beam therapy is not yet possible because of interplay effects between scanned beam and target motion which can cause severe mis-dosage. We have started a project to treat tumors that are subject to respiratory motion. A prototype beam application system for target tracking with the scanned pencil beam has been developed and commissioned.</p> <p>To facilitate treatment planning for tumors that are subject to organ motion, we have extended our standard treatment planning system TRiP to full 4D functionality. The 4D version of TRiP allows to calculate dose distributions in the presence of motion. Furthermore, for motion mitigation techniques tracking, gating, rescanning, and internal margins optimization of treatment parameters has been implemented. 4D calculations are based on 4D computed tomography data, deformable registration maps, organ motion traces, and beam scanning parameters.</p> <p>We describe the methods of our 4D treatment planning approach and demonstrate functionality of the system for phantom as well as patient data.</p>
url http://www.ro-journal.com/content/2/1/24
work_keys_str_mv AT rietzeleike 4dtreatmentplanningforscannedionbeams
AT bertchristoph 4dtreatmentplanningforscannedionbeams
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