A Sparse and Low-Rank Regression Model for Identifying the Relationships Between DNA Methylation and Gene Expression Levels in Gastric Cancer and the Prediction of Prognosis

A Sparse and Low-Rank Regression Model for Identifying the Relationships Between DNA Methylation and Gene Expression Levels in Gastric Cancer and the Prediction of Prognosis

DNA methylation is an important regulator of gene expression that can influence tumor heterogeneity and shows weak and varying expression levels among different genes. Gastric cancer (GC) is a highly heterogeneous cancer of the digestive system with a high mortality rate worldwide. The heterogeneous...

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Bibliographic Details
Main Authors: Yishu Wang, Lingyun Xu, Dongmei Ai
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
low-rank sparse regression model
DNA methylation
prognosis
gene expression
gastric cancer
Online Access:https://www.mdpi.com/2073-4425/12/6/854

Internet

https://www.mdpi.com/2073-4425/12/6/854

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