Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals

Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals

Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by ex vivo handling and the interference of highly abundant glob...

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Bibliographic Details
Main Authors: Yi Yang, Eric A. G. Blomme, Michael J. Liguori, Paul M. Jung, Amy C. Ditewig, Meagan M. Fricano
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:International Journal of Molecular Sciences
Subjects:
blood
biomarker
inflammation
transcriptomics
Online Access:http://www.mdpi.com/1422-0067/12/4/2502/

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