Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives

Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives

In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides...

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Bibliographic Details
Main Authors: A. Demirdağ, A. Cansız, M. Koparır
Format: Article
Language:English
Published: MDPI AG 2004-03-01
Series:Molecules
Subjects:
4H-1
2
4-triazole-3-thiols
azomethines
thiosemicarbazides.
Online Access:http://www.mdpi.com/1420-3049/9/4/204/
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spelling doaj-d62f1d43032e4310858ca4541a7663522020-11-24T23:02:38ZengMDPI AGMolecules1420-30492004-03-019420421210.3390/90400204Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol DerivativesA. DemirdağA. CansızM. KoparırIn this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and 9a-e. In addition, theazomethines 11a-d and 12a-d were prepared from the corresponding arylaldehydes and the4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The structures of allthe synthesized compounds were confirmed by elemental analyses, IR, 1H-NMR and13 C-NMR spectra.http://www.mdpi.com/1420-3049/9/4/204/4H-124-triazole-3-thiolsazomethinesthiosemicarbazides.
collection DOAJ
language English
format Article
sources DOAJ
author A. Demirdağ
A. Cansız
M. Koparır
spellingShingle A. Demirdağ
A. Cansız
M. Koparır
Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
Molecules
4H-1
2
4-triazole-3-thiols
azomethines
thiosemicarbazides.
author_facet A. Demirdağ
A. Cansız
M. Koparır
author_sort A. Demirdağ
title Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
title_short Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
title_full Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
title_fullStr Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
title_full_unstemmed Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives
title_sort synthesis of some new 4,5-substituted-4h-1,2,4-triazole-3-thiol derivatives
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2004-03-01
description In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and 9a-e. In addition, theazomethines 11a-d and 12a-d were prepared from the corresponding arylaldehydes and the4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The structures of allthe synthesized compounds were confirmed by elemental analyses, IR, 1H-NMR and13 C-NMR spectra.
topic 4H-1
2
4-triazole-3-thiols
azomethines
thiosemicarbazides.
url http://www.mdpi.com/1420-3049/9/4/204/
work_keys_str_mv AT ademirdaaay synthesisofsomenew45substituted4h124triazole3thiolderivatives
AT acansaaz synthesisofsomenew45substituted4h124triazole3thiolderivatives
AT mkoparaar synthesisofsomenew45substituted4h124triazole3thiolderivatives
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