PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation.

PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation.

Regenerated cartilage formed after Autologous Chondrocyte Implantation may be of suboptimal quality due to postulated hypertrophic changes. Parathyroid hormone-related peptide, containing the parathyroid hormone sequence (PTHrP 1-34), enhances cartilage growth during development and inhibits hypertr...

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Bibliographic Details
Main Authors: Marijn Rutgers, Frances Bach, Luciënne Vonk, Mattie van Rijen, Vanessa Akrum, Antonette van Boxtel, Wouter Dhert, Laura Creemers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213483

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https://doi.org/10.1371/journal.pone.0213483

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