G Protein-Coupled Receptors in the Mammalian Blood-Brain Barrier

G Protein-Coupled Receptors in the Mammalian Blood-Brain Barrier

The mammalian neurovascular unit (NVU) is comprised of neurons, glia, and vascular cells. The NVU is the nexus between the cardiovascular and central nervous system (CNS). The central component of the NVU is the blood-brain barrier (BBB) which consists of a monolayer of tightly connected endothelial...

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Bibliographic Details
Main Authors: Brock R. Pluimer, Mark Colt, Zhen Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neurovascular unit
G-protein coupled receptors
blood-brain barrier
neurodegenerative disease
drug development
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00139/full

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