Immunity and autoantibodies of a mouse strain with autistic-like behavior

Female and male mice of the BTBR T+Itpr3tf/J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG levels and generate high levels of IgG antibodies, including auto...

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Bibliographic Details
Main Authors: Mohammad Nizam Uddin, Yunyi Yao, Tapan Mondal, Rosemary Matala, Kevin Manley, Qishan Lin, David A. Lawrence
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266635462030034X