Essential statistical principles of clinical trials of pain treatments

Abstract. This article presents an overview of fundamental statistical principles of clinical trials of pain treatments. Statistical considerations relevant to phase 2 proof of concept and phase 3 confirmatory randomized trials investigating efficacy and safety are discussed, including (1) research...

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Bibliographic Details
Main Authors: Robert H. Dworkin, Scott R. Evans, Omar Mbowe, Michael P. McDermott
Format: Article
Language:English
Published: Wolters Kluwer 2021-01-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000863