A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders

SUMMARY Human peroxisome biogenesis disorders are lethal genetic diseases in which abnormal peroxisome assembly compromises overall peroxisome and cellular function. Peroxisomes are ubiquitous membrane-bound organelles involved in several important biochemical processes, notably lipid metabolism and...

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Bibliographic Details
Main Authors: Fred D. Mast, Jing Li, Maninder K. Virk, Sarah C. Hughes, Andrew J. Simmonds, Richard A. Rachubinski
Format: Article
Language:English
Published: The Company of Biologists 2011-09-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/5/659