Maternal obesity during the preconception and early life periods alters pancreatic development in early and adult life in male mouse offspring.

Maternal obesity during the preconception and early life periods alters pancreatic development in early and adult life in male mouse offspring.

Maternal obesity induced by a high fat (HF) diet may program susceptibility in offspring, altering pancreatic development and causing later development of chronic degenerative diseases, such as obesity and diabetes. Female mice were fed standard chow (SC) or an HF diet for 8 weeks prior to mating an...

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Bibliographic Details
Main Authors: Isabele Bringhenti, Jessica Andrade Moraes-Teixeira, Michelle Rabello Cunha, Fernanda Ornellas, Carlos Alberto Mandarim-de-Lacerda, Marcia Barbosa Aguila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561327?pdf=render

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