LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System

LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System

Leukocyte trafficking is a key event during autoimmune and inflammatory responses. The subarachnoid space (SAS) and cerebrospinal fluid are major routes for the migration of encephalitogenic T cells into the central nervous system (CNS) during experimental autoimmune encephalomyelitis (EAE), the ani...

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Main Authors: Silvia Dusi, Stefano Angiari, Enrica Caterina Pietronigro, Nicola Lopez, Gabriele Angelini, Elena Zenaro, Vittorina Della Bianca, Gabriele Tosadori, Francesca Paris, Antonella Amoruso, Tommaso Carlucci, Gabriela Constantin, Barbara Rossi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
lymphocyte function-associated antigen 1
Th1 and Th17 cells
intra-tissue motility
two-photon laser microscopy
experimental autoimmune encephalomyelitis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02436/full

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