Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast

Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast

Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism. Using time-lapse fluorescence microscopy in budding yeast, we fou...

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Bibliographic Details
Main Authors: Grant A King, Jay S Goodman, Jennifer G Schick, Keerthana Chetlapalli, Danielle M Jorgens, Kent L McDonald, Elçin Ünal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
meiosis
aging
nuclear pore complex
nucleolus
protein aggregation
quality control
Online Access:https://elifesciences.org/articles/47156

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