Stiffness Matters: Fine-Tuned Hydrogel Elasticity Alters Chondrogenic Redifferentiation

Stiffness Matters: Fine-Tuned Hydrogel Elasticity Alters Chondrogenic Redifferentiation

Biomechanical cues such as shear stress, stretching, compression, and matrix elasticity are vital in the establishment of next generation physiological in vitro tissue models. Matrix elasticity, for instance, is known to guide stem cell differentiation, influence healing processes and modulate extra...

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Bibliographic Details
Main Authors: Barbara Bachmann, Sarah Spitz, Barbara Schädl, Andreas H. Teuschl, Heinz Redl, Sylvia Nürnberger, Peter Ertl
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cartilage
chondrocytes
3D cell culture
extracellular matrix
hydrogel
Young’s modulus
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00373/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00373/full

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