Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different...

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Main Authors: Claire Mennan, Karina Wright, Atanu Bhattacharjee, Birender Balain, James Richardson, Sally Roberts
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/916136
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spelling doaj-d5ef3e13be5a485590ef69c0014117f02020-11-24T22:16:27ZengHindawi LimitedBioMed Research International2314-61332314-61412013-01-01201310.1155/2013/916136916136Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical CordClaire Mennan0Karina Wright1Atanu Bhattacharjee2Birender Balain3James Richardson4Sally Roberts5The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust & ISTM, Keele University, Oswestry, Shropshire SY10 7AG, UKThe Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust & ISTM, Keele University, Oswestry, Shropshire SY10 7AG, UKInstitute for Orthopaedics, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Oswestry SY10 7AG, UKInstitute for Orthopaedics, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Oswestry SY10 7AG, UKInstitute for Orthopaedics, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Oswestry SY10 7AG, UKThe Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust & ISTM, Keele University, Oswestry, Shropshire SY10 7AG, UKUmbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton’s jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.http://dx.doi.org/10.1155/2013/916136
collection DOAJ
language English
format Article
sources DOAJ
author Claire Mennan
Karina Wright
Atanu Bhattacharjee
Birender Balain
James Richardson
Sally Roberts
spellingShingle Claire Mennan
Karina Wright
Atanu Bhattacharjee
Birender Balain
James Richardson
Sally Roberts
Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
BioMed Research International
author_facet Claire Mennan
Karina Wright
Atanu Bhattacharjee
Birender Balain
James Richardson
Sally Roberts
author_sort Claire Mennan
title Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_short Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_full Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_fullStr Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_full_unstemmed Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
title_sort isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2013-01-01
description Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton’s jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.
url http://dx.doi.org/10.1155/2013/916136
work_keys_str_mv AT clairemennan isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
AT karinawright isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
AT atanubhattacharjee isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
AT birenderbalain isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
AT jamesrichardson isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
AT sallyroberts isolationandcharacterisationofmesenchymalstemcellsfromdifferentregionsofthehumanumbilicalcord
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