Implications of Polymorphisms in the BCKDK and GATA‐4 Gene Regions on Stable Warfarin Dose in African Americans

Implications of Polymorphisms in the BCKDK and GATA‐4 Gene Regions on Stable Warfarin Dose in African Americans

VKORC1 and CYP2C9 genotypes explain less variability in warfarin dose requirements in African Americans compared with Europeans. Variants in BCKDK and GATA‐4 gene regions, purported to regulate VKORC1 and CYP2C9 expression, have been shown to play an important role in warfarin dose requirements in E...

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Bibliographic Details
Main Authors: Salma A. Bargal, Jennifer N. Kight, Felipe Augusto de Oliveira, Mohamed H. Shahin, Taimour Langaee, Yan Gong, Issam S. Hamadeh, Rhonda M. Cooper-DeHoff, Larisa H. Cavallari
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12939

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