Propagation of temporal and rate signals in cultured multilayer networks

The nature of the signals that propagate through feedforward networks is not well understood. Here, the authors combine microfabrication, multilayer cortical cultures, and optogenetic stimulation to show that NMDA-mediated synaptic current generates a sustained phase of activity that propagates firi...

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Bibliographic Details
Main Authors: Jérémie Barral, Xiao-Jing Wang, Alex D. Reyes
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11851-0