ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans.

ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans.

Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule component is the Argonaute CSR-1, a small-RNA bin...

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Bibliographic Details
Main Authors: Karolina M Andralojc, Anne C Campbell, Ashley L Kelly, Markus Terrey, Paige C Tanner, Ian M Gans, Michael J Senter-Zapata, Eraj S Khokhar, Dustin L Updike
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5325599?pdf=render

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