Regulation of trypsin-like enzyme activity in the tissues of white rats with thiamine

• Main Authors: O. Ustjansky, S. Petrov, O. Budnyak, S. Gozhenk
• Format: Article
• Language: English
• Published: Taras Shevchenko National University of Kyiv 2016-11-01
• Series: Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ
• Subjects: thiamine, trypsin-like enzymes, organ specificity
• Online Access: http://biovestnik.com/index.php/biology/article/view/16

The effect of intramuscular thiamine injection on the activity of trypsin-like enzymes in the liver, kidneys, stomach and small intestine of white rats has been researched. In the organs of intact rats, the maximum activity of trypsin-like proteases has been established in the small intestine, and the minimum one in the liver. Thiamine parenteral administration leads to the decrease of trypsin-like protease activity in the liver, kidney and stomach, and the increase of the enzyme activity in the small intestine that suggests the possibility of non-coenzyme thiamine effect on the trypsin-like enzyme activity.