Genetic-Based Prediction of Disease Traits: Prediction is Very Difficult, Especially about the Future

Genetic-Based Prediction of Disease Traits: Prediction is Very Difficult, Especially about the Future

Translation of results from genetic findings to inform medical practice is a highly anticipated goal of human genetics. The aim of this paper is to review and discuss the role of genetics in medically-relevant prediction. Germline genetics presages disease onset and therefore can contribute progno...

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Bibliographic Details
Main Authors: Steven J Schrodi, Shubhabrata eMukherjee, Ying eShan, Gerard eTromp, John J Sninsky, Amy P Callear, Tonia C. Carter, Zhan eYe, Jonathan L Haines, Murray H Brilliant, Paul K Crane, Diane T Smelser, Robert C Elston, Daniel E Weeks
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Genetics
Subjects:
Human genetics
prognosis
genetic risk
clinical utility
predictive model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00162/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00162/full

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