Crumple: a method for complete enumeration of all possible pseudoknot-free RNA secondary structures.

The diverse landscape of RNA conformational space includes many canyons and crevices that are distant from the lowest minimum free energy valley and remain unexplored by traditional RNA structure prediction methods. A complete description of the entire RNA folding landscape can facilitate identifica...

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Bibliographic Details
Main Authors: Samuel Bleckley, Jonathan W Stone, Susan J Schroeder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531468?pdf=render