Novel Phenolic 1-aryl-3-arylamino-1-propanones: Synthesis and Characterization

A small collection of 1-aryl-3-arylamino-1-propanones having a phenolic moiety in their structure has been obtained by the replacement of the tertiary amino group in ketonic Mannich bases with (hetero)aromatic amines. The installment of the phenolic moiety took place either through the N-alkylation...

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Bibliographic Details
Main Author: Roman Gheorghe
Format: Article
Language:English
Published: Sciendo 2017-12-01
Series:Acta Chemica Iasi
Subjects:
Online Access:https://doi.org/10.1515/achi-2017-0015
Description
Summary:A small collection of 1-aryl-3-arylamino-1-propanones having a phenolic moiety in their structure has been obtained by the replacement of the tertiary amino group in ketonic Mannich bases with (hetero)aromatic amines. The installment of the phenolic moiety took place either through the N-alkylation of 4-aminophenol with ketonic Mannich base hydrochlorides, or via amine exchange in ketonic Mannich bases derived from either 2′-hydroxyacetophenone or 4′-hydroxyacetophenone.
ISSN:2067-2446