Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain

Comparative analysis of humoral immune responses and pathologies of BALB/c and C57BL/6 wildtype mice experimentally infected with a highly virulent Rodentibacter pneumotropicus (Pasteurella pneumotropica) strain

Abstract Background Mice are a natural host for Rodentibacter (R.) pneumotropicus. Despite specific monitoring, it is still one of the most important infectious agents in laboratory animals. The objective of this study was to determine the virulence of a prevalent pathotype of R. pneumotropicus and...

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Bibliographic Details
Main Authors: Juliane Fornefett, Jaqueline Krause, Kristin Klose, Felix Fingas, Rayk Hassert, Laurentiu Benga, Thomas Grunwald, Uwe Müller, Wieland Schrödl, Christoph Georg Baums
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Microbiology
Subjects:
Bronchopneumonia
RTX toxins
Th1/Th2 responses
Colonization
Animal model
Online Access:http://link.springer.com/article/10.1186/s12866-018-1186-8

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