PIWIL3 Forms a Complex with TDRKH in Mammalian Oocytes

PIWIL3 Forms a Complex with TDRKH in Mammalian Oocytes

P-element induced wimpy testis (PIWIs) are crucial guardians of genome integrity, particularly in germ cells. While mammalian PIWIs have been primarily studied in mouse and rat, a homologue for the human <i>PIWIL3 </i>gene is absent in the Muridae family, and hence the unique function of...

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Bibliographic Details
Main Authors: Minjie Tan, Helena T.A. van Tol, David Rosenkranz, Elke F. Roovers, Mirjam J. Damen, Tom A.E. Stout, Wei Wu, Bernard A.J. Roelen
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
oocyte
piRNA
transposon
PIWI
genomic integrity
mammal
Online Access:https://www.mdpi.com/2073-4409/9/6/1356

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