Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves

Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves

This data article reports on the in vivo biochemical activity of ethanolic extract of Thaumatococcus daniellii (Benn.) Benth leaves (ETD) in male Wistar rats at an oral dose of 500–1500 mg/kg daily for 14 days. Control groups were administered distilled water and Vitamin C (10 mg/kg; b.wt). Indices...

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Main Authors: Shalom Nwodo Chinedu, Franklyn Nonso Iheagwam, Boluwatife Taiwo Makinde, Babajide Oladipo Thorpe, Opeyemi Christianah Emiloju
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918308667
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spelling doaj-d5944b3b7afa45eba1b02a3e4a02b5322020-11-25T02:43:59ZengElsevierData in Brief2352-34092018-10-0120364370Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leavesShalom Nwodo Chinedu0Franklyn Nonso Iheagwam1Boluwatife Taiwo Makinde2Babajide Oladipo Thorpe3Opeyemi Christianah Emiloju4Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Corresponding authors.Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Corresponding authors.Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, NigeriaDepartment of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, NigeriaDepartment of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, NigeriaThis data article reports on the in vivo biochemical activity of ethanolic extract of Thaumatococcus daniellii (Benn.) Benth leaves (ETD) in male Wistar rats at an oral dose of 500–1500 mg/kg daily for 14 days. Control groups were administered distilled water and Vitamin C (10 mg/kg; b.wt). Indices of oxidative stress, dyslipidemia, liver injury and liver pathology were estimated in the plasma and organs after the investigation period. Oral treatment with ETD increased organ superoxide dismutase (SOD) activity, renal reduced glutathione (GSH) and plasma high density lipoprotein (HDL) concentrations while reducing plasma alanine transaminase (ALT) activity, plasma cholesterol (CHOL), bilirubin (DBIL) and organ malondialdehyde (MDA) concentrations (P<0.05). Data was supported by histological report showing no pathologic abnormality. This data indicate ethanolic extract of T. daniellii leaves shows antioxidant, hypolipidemic and hepatoprotective potential. Keywords: Thaumatococcus daniellii, in vivo, Oxidative stress, Antioxidant, Liver injury, Hypolipidemichttp://www.sciencedirect.com/science/article/pii/S2352340918308667
collection DOAJ
language English
format Article
sources DOAJ
author Shalom Nwodo Chinedu
Franklyn Nonso Iheagwam
Boluwatife Taiwo Makinde
Babajide Oladipo Thorpe
Opeyemi Christianah Emiloju
spellingShingle Shalom Nwodo Chinedu
Franklyn Nonso Iheagwam
Boluwatife Taiwo Makinde
Babajide Oladipo Thorpe
Opeyemi Christianah Emiloju
Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
Data in Brief
author_facet Shalom Nwodo Chinedu
Franklyn Nonso Iheagwam
Boluwatife Taiwo Makinde
Babajide Oladipo Thorpe
Opeyemi Christianah Emiloju
author_sort Shalom Nwodo Chinedu
title Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
title_short Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
title_full Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
title_fullStr Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
title_full_unstemmed Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves
title_sort data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of thaumatococcus daniellii (benn.) benth leaves
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2018-10-01
description This data article reports on the in vivo biochemical activity of ethanolic extract of Thaumatococcus daniellii (Benn.) Benth leaves (ETD) in male Wistar rats at an oral dose of 500–1500 mg/kg daily for 14 days. Control groups were administered distilled water and Vitamin C (10 mg/kg; b.wt). Indices of oxidative stress, dyslipidemia, liver injury and liver pathology were estimated in the plasma and organs after the investigation period. Oral treatment with ETD increased organ superoxide dismutase (SOD) activity, renal reduced glutathione (GSH) and plasma high density lipoprotein (HDL) concentrations while reducing plasma alanine transaminase (ALT) activity, plasma cholesterol (CHOL), bilirubin (DBIL) and organ malondialdehyde (MDA) concentrations (P<0.05). Data was supported by histological report showing no pathologic abnormality. This data indicate ethanolic extract of T. daniellii leaves shows antioxidant, hypolipidemic and hepatoprotective potential. Keywords: Thaumatococcus daniellii, in vivo, Oxidative stress, Antioxidant, Liver injury, Hypolipidemic
url http://www.sciencedirect.com/science/article/pii/S2352340918308667
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